Buy Modafinil Overnight

Buy Modafinil Overnight Modafinil is a wakefulness-promoting drug used to treat excessive sleepiness due to narcolepsy, obstructive sleep apnea, or shift work sleep disorder. Sometimes it is used off-label as a cognitive enhancer. Modafinil's exact mechanism is unclear, though it affects many neurotransmitter systems in the brain. Some studies suggest it may enhance performance on complex tasks in healthy individuals; however, no long-term studies have tested whether modafinil prevents cognitive decline or dementia. Modafinil is generally considered safe for most people with minor side effects such as headache, nausea, dizziness, insomnia, and anxiety.

Modafinil was originally developed in France by neurophysiologist professor Michel Jouvet and Lafon Laboratories. Modafinil originated with the late 1970s invention of a series of benzhydryl sulfinyl compounds, including adrafinil, which was first offered as an experimental treatment for narcolepsy in France in 1986. Modafinil is the primary metabolite of adrafinil, lacking the polar -OH group on its terminal amide,  and has similar activity to the parent drug but is much more widely used. It has been prescribed in France since 1994 under the name Modiodal , and in the US since 1998 as Provigil.

The addiction and dependence liabilities of modafinil are very low.  It shares biochemical mechanisms with addictive stimulant drugs, and some studies have reported it to have similar mood-elevating properties, although to a lesser degree. It is not clear whether these effects are any more different than the ones from caffeine. Modafinil does not appear to produce euphoric effects nor deviations (i.e. abuse) from assigned dosages to the patient.

Modafinil is classified by the United States FDA as a schedule IV controlled substance, a category for drugs with valid medical uses and low addiction potential. The International Narcotics Control Board does not consider modafinil a narcotic  nor a psychotropic substance. In fact, modafinil may increase abstinence rates in a subgroup of cocaine addicts while modafinil-related discontinuation adverse effects are no different from placebo.

Serious Dermatologic Reactions

Serious skin rash (e.g., Stevens-Johnson syndrome [SJS]) requiring hospitalization and drug discontinuance was reported in adult and pediatric patients receiving modafinil.

Severe rash (e.g., possible SJS, multiorgan hypersensitivity reaction), sometimes associated with fever and other abnormalities (e.g., vomiting, leukopenia), reported in pediatric clinical trials. No serious rashes were reported in clinical trials in adults. Serious or life-threatening rash (e.g., SJS, toxic epidermal necrolysis [TEN], drug rash with eosinophilia, and systemic symptoms [DRESS]) is reported rarely during postmarketing experience. Modafinil is not approved for use in pediatric patients for any indication. (See Pediatric Use under Cautions.)

No known risk factors predict the occurrence or severity of the rash. Nearly all cases occurred within 1–5 weeks following initiation of therapy, but cases were also reported after prolonged (e.g., 3 months) treatment.

Benign rashes also occur with modafinil; not possible to predict which rashes will become serious. Therefore, discontinue the drug at the first sign of rash unless clearly not drug-related. (See Advice to Patients.) Rash may become potentially life-threatening or permanently disabling or disfiguring despite drug discontinuance.

The most common side effects of modafinil are as follows: headache, back pain, nausea, nervousness, stuffy nose, diarrhea, feeling anxious, trouble sleeping, dizziness, and upset stomach.

Other serious side effects include: a serious rash or allergic reaction including Stevens-Johnson Syndrome; rapid swelling beneath the skin; new mental health problems such as depression, anxiety, aggression, hallucinations, and thoughts of suicide; and symptoms of a heart problem including chest pain, abnormal heartbeat, and trouble breathing. In rare cases, modafinil can create a multi-organ hypersensitivity reaction, which can be life-threatening. Stop taking modafinil and seek medical attention immediately if you experience any of these serious side effects.

Taking modafinil may impair your ability to drive, operate machinery, or perform other potentially dangerous tasks. If side effects are bothersome, or do not go away, talk to your doctor. Most people taking this medication do not experience any of these side effects.

Report to your doctor any heart-related problems or a family history of heart or blood pressure problems. Patients with structural cardiac abnormalities and other serious heart problems have experienced cardiac arrest while taking modafinil. Stimulants, like modafinil, can increase blood pressure and heart rate. Physicians should monitor these vital signs closely during treatment. Call your doctor immediately if you experience warning signs such as chest pain, shortness of breath, or fainting while taking modafinil.

Modafinil comes as a tablet to take by mouth. It is usually taken once a day with or without food. If you are taking modafinil to treat narcolepsy or OSAHS, you will probably take it in the morning. If you are taking modafinil to treat shift work sleep disorder, you will probably take it 1 hour before the beginning of your work shift. Take modafinil at the same time every day. Do not change the time of day that you take modafinil without talking to your doctor. Talk to your doctor if your work shift does not begin at the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take modafinil exactly as directed.

Modafinil may be habit-forming. Do not take a larger dose, take it more often, or take it for a longer period of time than prescribed by your doctor.

Modafinil may decrease your sleepiness, but it will not cure your sleep disorder. Continue to take modafinil even if you feel well-rested. Do not stop taking modafinil without talking to your doctor.

Modafinil should not be used in place of getting enough sleep. Follow your doctor's advice about good sleep habits. Continue to use any breathing devices or other treatments that your doctor has prescribed to treat your condition, especially if you have OSAHS.

Usual Adult Dose for Narcolepsy:

200 mg orally once a day in the morning

Comments:

-In obstructive sleep apnea (OSA), this drug is not a treatment for the underlying obstruction.

-If continuous positive airway pressure (CPAP) is the treatment of choice for excessive sleepiness, a maximal effort to treat with CPAP for an adequate period of time should be made prior to and during treatment with this drug.

Use: Treatment to improve wakefulness in patients with excessive sleepiness associated with narcolepsy and OSA.

Usual Adult Dose for Obstructive Sleep Apnea/Hypopnea Syndrome:

200 mg orally once a day in the morning

Comments:

-In obstructive sleep apnea (OSA), this drug is not a treatment for the underlying obstruction.

-If continuous positive airway pressure (CPAP) is the treatment of choice for excessive sleepiness, a maximal effort to treat with CPAP for an adequate period of time should be made prior to and during treatment with this drug.

Use: Treatment to improve wakefulness in patients with excessive sleepiness associated with narcolepsy and OSA.

Usual Adult Dose for Shift Work Sleep Disorder:

200 mg orally once a day, approximately 1 hour prior to the start of the work shift

Use: Treatment to improve wakefulness in patients with excessive sleepiness associated with shift work disorder.

Do not take this medicine with any of the following medications:

• amphetamine or dextroamphetamine
• dexmethylphenidate or methylphenidate
• medicines called MAO Inhibitors like Nardil, Parnate, Marplan, Eldepryl
• pemoline
• procarbazine
• This medicine may also interact with the following medications:
• antifungal medicines like itraconazole or ketoconazole
• barbiturates like phenobarbital
• birth control pills or other hormone-containing birth control devices or implants
• carbamazepine
• cyclosporine
• diazepam
• medicines for depression, anxiety, or psychotic disturbances
• phenytoin
• propranolol
• triazolam
• warfarin

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.